miR-101a and miR-30b contribute to inflammatory cytokine-mediated β-cell dysfunction
نویسندگان
چکیده
منابع مشابه
Phagocytosis in Myeloid Inflammatory Cells miR-24, miR-30b, and miR-142-3p Regulate
Micro-RNAs (miRNAs) are small noncoding RNAs that regulate various biological pathways. As their role in phagocytosis remains poorly understood, we investigated their impact on phagocytosis in myeloid inflammatory cells. Seven miRNAs (miR-24,-30b,-101, 142-3p,-652-3p,-652-5p, and-1275) that were differentially expressed during monocyte to macrophage (Mw) and monocyte to dendritic cell (DC) diff...
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Antigen uptake, processing and presentation by antigen presenting cells (APCs) are tightly coupled processes which consequently lead to the activation of innate and adaptive immune responses. However, the regulatory role of microRNA (miRNAs) in these critical pathways is poorly understood. In this study, we show that overexpression of miR-24, miR-30b and miR-142-3p attenuates uptake and process...
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ژورنال
عنوان ژورنال: Laboratory Investigation
سال: 2015
ISSN: 0023-6837,1530-0307
DOI: 10.1038/labinvest.2015.112